Pathway to Life Saving Science


 The Serious Challenges

Shortage of Human Organs

The United States as well as many other countries faces a dramatic shortage of available organs for transplant.  More than 100,000 patients now reside on the national transplant waiting list. Wait times can be significant and many patients in need of therapy are not even placed on a waiting list due to their physician’s expectation that they would never receive an opportunity for a transplant. This shortage of human organs is a serious challenge which must be addressed and solved.


High Transplant Costs

Patients/Insurers face significant,continual increasing costs associated with organ transplant. A single organ transplant can range in cost from six to seven figures and the annual, ongoing cost of immunosupressive drugs is more than $11,000 and in some instances can reach $25,000 per year depending upon the specific medication regimen (ASTS Fact Sheet).










The Clear Opportunities

To Save Lives

Dramatic strides have been made in tissue engineering sciences, and there is an opportunity to accelerate these advances to drive the eventual clinical impact that can be achieved. Kidney, liver, pancreas, heart muscle, and other tissues can be produced in small pilot research studies now, and simpler tissues such as bladder and trachea are already being transplanted into patients. A clear opportunity exists NOW to push this gamechanging science to the finish line. 



Improve Costs/Quality of Life

Achieving the creation of human organs from a patients own tissues would significantly impact both the timing of when transplant can occur and the availability of needed organs. In addition, for these organs the need for costly post transplant immunosupressive treatment (if needed at all) is expected to be significantly less.The expectation is that a patients body will accept and not be likely to reject re-transplant of an organ made of its own tissues and cells. 


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